Anti-VEGF
Humanized Monoclonal Antibody

The anti-VEGF antibody is an inhibitor 
of angiogenesis (blood-vessel growth)
that may hinder the growth of cancer tumors 
by starving their blood supply. Genentech is 
investigating this antibody in Phase II

Vascular endothelial growth factor
(VEGF) is a natural protein that promotes angiogenesis
(blood vessel growth).
VEGF couldpotentially benefit patients who have a
heart that is functioning but has a blocked blood 
supply due to artherioscleroticcoronar

Smart materials would be made of nanomachines, 
typically microscopic—with features any size,
down to atomic dimensions. Such machines would
have more or less, the same components as macro,
or familiar "normal" sized machines with
recognizable gears, 
bearings, motors, levers and belts... (except for all the nanocomputers).

This is somewhat helpful to the engineer 
designing smart materials with a myriad of 
functions like shape changing and distributing 
fluids and gas—say for environmental control in 
a paper thin space suit that actively moves with the body or Drexler's smart paint.
Open a can and splat some on a wall. The paint
spreads itself across the surface using microscopic
machines and changes color on command or
becomes a wall sized 3-D television... Then again, 
the whole wall may as well be smart material changing 
texture or windows on command.

The point here... one can visualize the machines
needed to do such a job: little tractors with sticky
wheels, connection struts and cables to other 
machines. Actually, most of this can be done today, only
on a much larger scale and at great expense
(this is where the novel economics of self replicating 
machines plugs in). The transition for an engineer,
is using more machines with much smaller parts and 
the luxury of vast computing power. 
These differences yield more great utility.

Gears made of Buckytubes are great
nanomachine components... Buckytubes are carbon graphite 
sheets rolled into a tube (looks like tubes of chicken wire), 
and are "like" carbon in its diamond form, 
but with ALL available bonding strength aligned on one axis.
These tubes are stronger than diamond
fiber, and the strongest fiber possible with matter,
so we're starting out with real racehorse material.
Globus and Team designs are chemically stable, 
very tough and varied in geometry, including gears made 
from "nested" Buckytubes or tubs inside of 
tubes. Such a gear would be stiffer and suited for a "long" 
drive shaft. And talk about performance...